Endocrine Abstracts

The risk of malignancy in thyroid nodules correlates with the presence of ultrasound features. In adults, ultrasound risk-classification systems have been proposed to indicate the need for further invasive diagnosis. Furthermore, elastography has been shown to support differential diagnosis of thyroid nodules. The purpose of our study was to assess the application of the American Thyroid Association (ATA) and British Thyroid Association (BTA) ultrasound risk-classification sys...

Graves’s disease is the most common type of autoimmune hyperthyroidism. Numerous studies indicate different factors contributing to the onset of the disease. Despite years of research, the exact pathomechanism of Graves’ disease still remains unresolved, especially in the context of immune response. B cells can play a dual role in autoimmune reactions, on the one hand, as a source of autoantibody mainly targeted in the thyroid hormone receptor (TSHR) and, on the othe...

Introduction: Hashimoto’s thyroiditis (HT) is the most frequent cause of thyroid disfunction in children and its incidence is increasing. Although thyroid cancer is an uncommon childhood malignancy with a reported incidence of about 0.59 cases per 100,000, there are data suggesting the comorbidity of papillary thyroid carcinoma with autoimmune thyroiditis (AIT) in children. Ultrasound elastography is a non-invasive imaging, based on estimation of mechanical properties (el...